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CRISPR/Cas9 genome editing techniques have the potential to treat previously untreatable inherited genetic disorders of vision by correcting mutations that cause these afflictions. Using a prime editor, Qin et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20220776) restored visual functions in a mouse model (rd10) of retinitis pigmentosa.
Gene Editing, Biomedical and clinical sciences, Biomedical and Clinical Sciences, Animal, Human Genome, Immunology, Health sciences, Eye, Medical and Health Sciences, Insights, Mice, Disease Models, Animal, Rare Diseases, Disease Models, Mutation, Genetics, Animals, CRISPR-Cas Systems, Eye Disease and Disorders of Vision, Retinitis Pigmentosa, Ophthalmology and Optometry
Gene Editing, Biomedical and clinical sciences, Biomedical and Clinical Sciences, Animal, Human Genome, Immunology, Health sciences, Eye, Medical and Health Sciences, Insights, Mice, Disease Models, Animal, Rare Diseases, Disease Models, Mutation, Genetics, Animals, CRISPR-Cas Systems, Eye Disease and Disorders of Vision, Retinitis Pigmentosa, Ophthalmology and Optometry
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 4 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |