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Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering

descriptionPublicationkeyboard_double_arrow_right Article 18 Mar 2019 United States English Publisher:Rockefeller University PressJournal:Journal of Cell Biology, volume 218, pages 1,089-1,091 (issn: 0021-9525, eissn: 1540-8140, Copyright policy )Funded by:NIH | Elucidating the relations...
Authors: Truc B. Nguyen; James A. Olzmann;

doi: 10.1083/jcb.201902160

pmid: 30886057

pmc: PMC6446839

Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering

Abstract

Lipid droplets (LDs) are hubs for lipid metabolism that form membrane contact sites with multiple organelles. In this issue, Hariri et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808119) reveal the functions of Mdm1-mediated endoplasmic reticulum (ER)–LD tethering in yeast and Datta et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201808133) identify a role for the Mdm1 orthologue, Snx14, as an ER–LD tether that regulates lipid metabolism in human cells.

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Keywords

570, Saccharomyces cerevisiae Proteins, 612, Lipid Droplets, Saccharomyces cerevisiae, Biological Sciences, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, Medical and Health Sciences, Intermediate Filament Proteins, Commentaries, Homeostasis, Humans, Sorting Nexins, Developmental Biology

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 16
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
16
Top 10%
Average
Top 10%
Green
hybrid