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The INs and OUTs of mitofusins

descriptionPublicationkeyboard_double_arrow_right Article 18 Jan 2018 Italy English Publisher:Rockefeller University PressJournal:Journal of Cell Biology, volume 217, pages 439-440 (issn: 0021-9525, eissn: 1540-8140, Copyright policy )
Authors: Giacomello, Marta; Scorrano, Luca;

doi: 10.1083/jcb.201801042

pmid: 29348146

pmc: PMC5800822

handle: 11577/3265143

The INs and OUTs of mitofusins

Abstract

Mitofusins are outer membrane proteins essential for mitochondrial fusion. Their accepted topology posits that both N and C termini face the cytoplasm. In this issue, Mattie et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201611194) demonstrate instead that their C termini reside in the intermembrane space. These findings call for a revision of the current models of mitochondrial fusion.

Country
Italy
Related Organizations
Keywords

Commentaries, Membrane Proteins, Cell Biology, Intracellular Membranes, Mitochondrial Dynamics, Oxidation-Reduction, Mitochondria

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Top 10%
Average
Top 10%
Green
hybrid
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