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Stability of Pilocarpine Ophthalmic Solutions

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1999 English Publisher:Informa UK LimitedJournal:Drug Development and Industrial Pharmacy, volume 25, pages 801-805 (issn: 0363-9045, eissn: 1520-5762, Copyright policy )
Authors: C, Pilatti; M C, Torre; C, Chiale; M, Spinetto;

doi: 10.1081/ddc-100102241

pmid: 10349567

Stability of Pilocarpine Ophthalmic Solutions

Abstract

The stability of pilocarpine and pilocarpine-timolol eyedrop preparations available on the Argentine market was studied. A high-performance liquid chromatographic method that allows the estimation of pilocarpine in the presence of degradation products was used for the study according to the preestablished design. It was found that pilocarpine solutions are stable, while pilocarpine in association with timolol shows significant degradation.

Keywords

Argentina, Pilocarpine, Solutions, Drug Stability, Parasympathomimetics, Sympatholytics, Timolol, Drug Interactions, Ophthalmic Solutions, Chromatography, High Pressure Liquid

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Average
Average
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