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Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient

Authors: Sun, Jing; Zhu, Airu; Li, Heying; Zheng, Kui; Zhuang, Zhen; Chen, Zhao; Shi, Yongxia; +22 Authors

Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient

Abstract

SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its’ own patient sera. Appropriate precautions should be taken to avoid transmission from urine.

Related Organizations
Keywords

Male, COVID-19 ; virus isolation ; urine ; transmission ; SARS-CoV-2, Letter, Epidemiology, Immunology, Pneumonia, Viral, Infectious and parasitic diseases, RC109-216, Genome, Viral, Microbiology, Betacoronavirus, Virology, Drug Discovery, Chlorocebus aethiops, Animals, Humans, Pandemics, Vero Cells, Aged, virus isolation, Reverse Transcriptase Polymerase Chain Reaction, SARS-CoV-2, transmission, COVID-19, General Medicine, urine, QR1-502, Infectious Diseases, Parasitology, Coronavirus Infections

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    296
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
296
Top 0.1%
Top 1%
Top 0.1%
Green
gold