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A rare case of eptifibatide-induced thrombocytopenia

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 04 Mar 2021Publisher:Greater Baltimore Medical CenterJournal:Journal of Community Hospital Internal Medicine Perspectives, volume 11, pages 269-272 (eissn: 2000-9666,

Authors: Khalil Kamar; Kira MacDougall; Mira Alsheikh; Sara Parylo; Yevgeniy Skaradinskiy;

doi: 10.1080/20009666.2021.1871802

pmid: 33889336

pmc: PMC8043518

A rare case of eptifibatide-induced thrombocytopenia

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Abstract

Eptifibatide is a glycoprotein (GP) IIb/IIIa receptor antagonist, used for the treatment of acute coronary syndrome with high-risk features or ongoing ischemia. Several case reports have described thrombocytopenia as a rare side effect of eptifibatide administration. The exact mechanism remains unclear but may be due to immune destruction of circulating platelets in the peripheral blood. We present the case of acute-onset severe thrombocytopenia in a 76-year-old female undergoing percutaneous coronary intervention.

Related Organizations

Staten Island University Hospital
United States

Keywords

drug-induced thrombocytopenia, thrombocytopenia, Case Report, glycoprotein iib/iiia receptor antagonist, Internal medicine, RC31-1245, eptifibatide, acute coronary syndrome

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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average