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Thermodynamic Studies of RNA Stability

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1984Publisher:Informa UK LimitedJournal:Journal of Biomolecular Structure and Dynamics, volume 1, pages 1,229-1,242 (issn: 0739-1102, eissn: 1538-0254, Copyright policy )
Authors: David R. Hickey; Matthew Petersheim; Susan M. Freier; Douglas H. Turner;

doi: 10.1080/07391102.1984.10507514

pmid: 6086053

Thermodynamic Studies of RNA Stability

Abstract

Enthalpies and entropies of helix stabilization due to addition of 3' terminal unpaired nucleotides to a CCGG or GGCC core double helix are derived from UV melting studies. The results suggest stacking provides a significant fraction of the free energy of a terminal base pair. The effects of temperature, aggregation, and ionic strength on the determination of thermodynamic parameters are considered. Helix propagation parameters are revised and extended based on recent additions to the data set.

Related Organizations
Keywords

Base Composition, Oligoribonucleotides, Osmolar Concentration, Nucleic Acid Conformation, RNA, Thermodynamics

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
53
Top 10%
Top 1%
Top 10%
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