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Lipid peroxidation in eclampsia

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1997 English Publisher:Informa UK LimitedJournal:Journal of Obstetrics and Gynaecology, volume 17, pages 132-133 (issn: 0144-3615, eissn: 1364-6893,

Authors: G J Hofmeyr; A M Gu Lmezoglu; M M J Oosthuizen;

doi: 10.1080/01443619750113645

pmid: 15511799

Lipid peroxidation in eclampsia

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Abstract

In order to investigate the extent of lipid peroxidation in hypertensive disorders of pregnancy, a case-control study was designed. Eight eclamptic women were matched with women with severe pre-eclampsia (n = 8) and healthy pregnant controls (n = 8). Lipid peroxidation was measured by the malondialdehyde thiobarbituric acid reactive assay (MDA-TBAR) and expressed as nmol/ml. Both severe pre-eclampsia and eclampsia groups had significantly higher MDA-TBAR levels than healthy pregnant women. Eclamptic women before delivery had highest MDA-TBAR levels which decreased after delivery.

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University of the Witwatersrand
South Africa

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