This commentary is about the article by Feng, Cho, and Doolittle (1), a paper that addresses genealogical relationships between the three domains of organisms. First, however, I would like to be as forthcoming as possible on issues of nepotism and reveal another genealogy—that relating this paper’s senior author and me. Russell F. Doolittle and I recently have ascertained that we descend from a remote common ancestral couple—Ebeneezer and Hannah (nee Hall) Doolittle–via eight intermediate nodes on Russell’s side and seven, including two more Ebeneezers, on mine. We share Y chromosomes, if there have been no adoptions or other irregularities in either lineage, but eight generations should surely be enough to attenuate bias!