Sufficient evidence has accumulated to warrant the expansion of condom use research in several additional directions. Possible risk compensation pertaining to human papillomavirus vaccination and vaginal microbicides is one example. A second area of needed research involves the question of when couples can be advised to safely discontinue condom use given that ‘lifelong’ condom use is not a realistic goal for most people. A third example is intensified research designed to identify more effective means of mass marketing condoms and their use as a health-protective behaviour. As the AIDS and sexually transmissible infection pandemics persist, intensified condom promotion research is an ethical imperative.