
doi: 10.1071/ch9830779
Reduction of N-substituted azetidin-2-ones to N-substituted azetidines was accomplished rapidlyand in good yield with diborane in tetrahydrofuran and with alane in ether. The stereochemistryof the ring substituents was retained under the reaction conditions. 3-Aminopropanol derivativesformed by reductive ring cleavage were sometimes obtained as by-products in diborane reductionsbut not in alane reductions. The reductions of fourteen azetidin-2-ones to azetidines with diboraneand eighteen with alane are reported.
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