1,2,4-Triazol-3-ylpyridines

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1975 English Publisher:CSIRO PublishingJournal:Australian Journal of Chemistry, volume 28, pages 2,543-2,546 (issn: 0004-9425, eissn: 1445-0038,

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Authors: EJ Browne;

doi: 10.1071/ch9752543

1,2,4-Triazol-3-ylpyridines

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Abstract

A series of N-unsubstituted 1,2,4-triazol-3-ylpyridines was prepared for antiarthritic testing. Weak and scattered antiinflammatory activity was observed, with no clear structure-activity relationships. Some of the compounds, notably the 5-pyridyl-1,2,4-triazole-3-carboxylic acids, showed infrared bands characteristic of strong hydrogen bonding.

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