This work was focused on new drug-release potentials associated with phospholipid-bilayer structures and magnetic field effects, as it were, a liposomal nanoparticle model with reaction field-dependent spin-correlated radical pair mechanisms. The release potentials were evaluated by measuring the spectral changes after photoexcitation of anticancer flutamide in the liposomal membrane, as well as utilizing 31P-NMR signals which refers to a paramagnetic Eu-induced shift technique. As it turned out, a close connection between magnetic field effects and Eu3+ osmosis was observed depending on physicochemical reaction field, magnetic field strength, and so on. Reaction field-dependent spin-correlated radical pair mechanisms will find a new light in the future of liposomal drug-delivery system. Not only that, but this innovative methodology must be one of the most adaptable techniques, which may be able to analogize the ultrastructural state of molecular nanoenvironments swiftly and easily.