The “nano-indentation continuous stiffness measurement technique” has been employed to analyze the failure dynamics of mesoporous SiO2 based material (Vycor). The depth dependence of the indentation hardness (H), elastic modulus (E), and elastoplastic parameter (S2/P) shows crackling noise, which has been analyzed to monitor the jerky strain release. The noise is power law distributed with exponents near ∼1.5 over several decades, confirming avalanche criticality. This value is in good agreement with literature results obtained by other techniques and with earthquake statistics.