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Biomicrofluidics
Article
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Lirias
Article . 2016
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Biomicrofluidics
Article . 2016 . Peer-reviewed
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Biomicrofluidics
Article . 2016
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Simple microfluidic stagnation point flow geometries

Authors: Dockx, Greet; Verwijlen, Tom; Sempels, Wouter; Nagel, Mathias; Moldenaers, Paula; Hofkens, Johan; Vermant, Jan;

Simple microfluidic stagnation point flow geometries

Abstract

A geometrically simple flow cell is proposed to generate different types of stagnation flows, using a separation flow and small variations of the geometric parameters. Flows with high local deformation rates can be changed from purely rotational, over simple shear flow, to extensional flow in a region surrounding a stagnation point. Computational fluid dynamic calculations are used to analyse how variations of the geometrical parameters affect the flow field. These numerical calculations are compared to the experimentally obtained streamlines of different designs, which have been determined by high speed confocal microscopy. As the flow type is dictated predominantly by the geometrical parameters, such simple separating flow devices may alleviate the requirements for flow control, while offering good stability for a wide variety of flow types.

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Keywords

DYNAMICS, Biochemistry & Molecular Biology, DEVICES, SUSPENSIONS, Biophysics, 0915 Interdisciplinary Engineering, Biochemical Research Methods, 4012 Fluid mechanics and thermal engineering, 0203 Classical Physics, Physics, Fluids & Plasmas, BREAKUP, DROP DEFORMATION, Nanoscience & Nanotechnology, Science & Technology, 1007 Nanotechnology, Physics, 4-ROLL MILL, COALESCENCE, Physical Sciences, CELLS, Science & Technology - Other Topics, VISUALIZATION, SHEAR, Life Sciences & Biomedicine

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    7
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Top 10%
Average
Average
Green
bronze