descriptionPublicationkeyboard_double_arrow_right Article 12 Jan 2006 English Publisher:Massachusetts Medical SocietyJournal:New England Journal of Medicine, volume 354, pages 166-178 (issn: 0028-4793, eissn: 1533-4406,

Authors: William E. Evans; Ching-Hon Pui;

doi: 10.1056/nejmra052603

pmid: 16407512

Treatment of Acute Lymphoblastic Leukemia

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Abstract

Although the overall cure rate of acute lymphoblastic leukemia (ALL) in children is about 80 percent, affected adults fare less well. This review considers recent advances in the treatment of ALL, emphasizing issues that need to be addressed if treatment outcome is to improve further.

Related Organizations

St. Jude Children's Research Hospital
United States
University of Tennessee System
United States
University of Tennessee Health Science Center
United States

Keywords

Adult, Adolescent, Gene Expression Profiling, Remission Induction, Anti-Inflammatory Agents, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Prognosis, Combined Modality Therapy, Risk Assessment, Survival Analysis, Dexamethasone, Central Nervous System Neoplasms, Methotrexate, Antineoplastic Combined Chemotherapy Protocols, Asparaginase, Humans, Child, Stem Cell Transplantation

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