descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2001 English Publisher:Massachusetts Medical SocietyJournal:New England Journal of Medicine, volume 345, pages 1,318-1,330 (issn: 0028-4793, eissn: 1533-4406,

Authors: E, Mylonakis; S B, Calderwood;

doi: 10.1056/nejmra010082

pmid: 11794152

Infective Endocarditis in Adults

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Abstract

The clinical features of this complex infection have changed in the past several decades. It is now an infection of older people, and mitral-valve prolapse is the most common predisposing cardiovascular problem in developed countries. In contrast, rheumatic heart disease is an important predisposing problem in developing countries. This review article provides a comprehensive assessment of this serious infectious disease, including diagnostic challenges, cardiovascular and neurologic complications, and approaches to therapy.

Related Organizations

Massachusetts General Hospital
United States
Harvard University
United States

Keywords

Adult, Heart Failure, Prosthesis-Related Infections, Endocarditis, Bacteremia, Endocarditis, Bacterial, Microbial Sensitivity Tests, Staphylococcal Infections, Combined Modality Therapy, Anti-Infective Agents, Mycoses, Central Nervous System Diseases, Echocardiography, Recurrence, Risk Factors, Heart Valve Prosthesis, Streptococcal Infections, Humans

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