
pmid: 29342393
(Abstracted from N Engl J Med 2018;378:230–240) The majority of patients with ovarian cancer (OC) receive an initial diagnosis of advanced disease that has spread from the ovaries to the peritoneal surface. The most effective treatment for patients with advanced disease is cytoreductive surgery followed by systemic chemotherapy.
PHARMACOKINETICS, Paclitaxel, Clinical Trial, Phase III, 610, Radboud University Medical Center, GYNECOLOGIC-ONCOLOGY-GROUP, Carcinoma, Ovarian Epithelial, COLORECTAL-CANCER, Carboplatin, NEOADJUVANT CHEMOTHERAPY, CISPLATIN, Obstetrics and Gynaecology, Antineoplastic Combined Chemotherapy Protocols, Journal Article, Humans, Neoplasms, Glandular and Epithelial, Aged, Neoplasm Staging, Ovarian Neoplasms, OUTCOMES, Research Support, Non-U.S. Gov't, General Medicine, Cytoreduction Surgical Procedures, Hyperthermia, Induced, Middle Aged, PHASE-III, Combined Modality Therapy, Survival Analysis, Radboudumc 17: Women's cancers RIMLS: Radboud Institute for Molecular Life Sciences, RANDOMIZED-TRIAL, PERITONEAL CARCINOMATOSIS, Intention to Treat Analysis, Multicenter Study, CYTOREDUCTIVE SURGERY, Randomized Controlled Trial, Female, Cisplatin
PHARMACOKINETICS, Paclitaxel, Clinical Trial, Phase III, 610, Radboud University Medical Center, GYNECOLOGIC-ONCOLOGY-GROUP, Carcinoma, Ovarian Epithelial, COLORECTAL-CANCER, Carboplatin, NEOADJUVANT CHEMOTHERAPY, CISPLATIN, Obstetrics and Gynaecology, Antineoplastic Combined Chemotherapy Protocols, Journal Article, Humans, Neoplasms, Glandular and Epithelial, Aged, Neoplasm Staging, Ovarian Neoplasms, OUTCOMES, Research Support, Non-U.S. Gov't, General Medicine, Cytoreduction Surgical Procedures, Hyperthermia, Induced, Middle Aged, PHASE-III, Combined Modality Therapy, Survival Analysis, Radboudumc 17: Women's cancers RIMLS: Radboud Institute for Molecular Life Sciences, RANDOMIZED-TRIAL, PERITONEAL CARCINOMATOSIS, Intention to Treat Analysis, Multicenter Study, CYTOREDUCTIVE SURGERY, Randomized Controlled Trial, Female, Cisplatin
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