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Bisphosphonates for Osteoporosis

Name: Bisphosphonates for Osteoporosis
Creator: Murray J. Favus
Keywords: Fractures, Bone, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Bone Density Conservation Agents, Diphosphonates, Humans, Female, Osteoporosis, Postmenopausal, Aged

descriptionPublicationkeyboard_double_arrow_right Article 18 Nov 2010 English Publisher:Massachusetts Medical SocietyJournal:New England Journal of Medicine, volume 363, pages 2,027-2,035 (issn: 0028-4793, eissn: 1533-4406,

Authors: Murray J. Favus;

doi: 10.1056/nejmct1004903

pmid: 21083387

Bisphosphonates for Osteoporosis

- Summary
- Subjects
- Metrics

Abstract

A 67-year-old woman is referred by her primary care physician for treatment of osteoporosis and progressive bone loss. Oral bisphosphonate therapy is recommended. Bisphosphonates suppress bone resorption by interfering with osteoclast activity. Several of these agents have been shown to prevent fractures and increase bone mineral density in patients with osteoporosis. Long-term bisphosphonate therapy has been associated with osteonecrosis of the jaw and atypical femur fractures.

Related Organizations

University of Chicago
United States

Keywords

Fractures, Bone, Structure-Activity Relationship, Bone Density Conservation Agents, Diphosphonates, Humans, Female, Osteoporosis, Postmenopausal, Aged

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	190
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%