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Nicking Glaucoma with Nicotinamide?

descriptionPublicationkeyboard_double_arrow_right Article 25 May 2017Publisher:Massachusetts Medical SocietyJournal:New England Journal of Medicine, volume 376, pages 2,079-2,081 (issn: 0028-4793, eissn: 1533-4406,

Authors: George A. Cioffi; Jeffrey M. Liebmann;

doi: 10.1056/nejmcibr1702486

pmid: 28538117

Nicking Glaucoma with Nicotinamide?

- Summary
- Subjects
- Metrics

Abstract

A mouse model of glaucoma implicates mitochondrial dysfunction resulting from a deficit in retinal nicotinamide adenine dinucleotide — together with elevated intraocular pressure — as causing susceptibility to glaucoma.

Related Organizations

Columbia University Medical Center
United States

Keywords

Niacinamide, Administration, Oral, Gene Expression, Glaucoma, Genetic Therapy, NAD, Retina, Mitochondria, Disease Models, Animal, Mice, Vitamin B Complex, Animals, Humans, Intraocular Pressure

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	18
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%