A NUMBER of apparently nonspecific and unrelated serologic reactions are known to occur in patients with viral hepatitis, and the descriptions of these have been reviewed elsewhere.1 Among the various studies that have been made were attempts to demonstrate agglutinins for erythrocytes, and early reports described a heterophil antibody in the serums of some patients during the acute phase of hepatitis that agglutinated sheep erythrocytes. This antibody was apparently different from that found in infectious mononucleosis and could be differentiated from it by absorption on guinea-pig kidney.2 , 3 Subsequent studies by Bang4 indicated that old stored serums of patients with hepatitis . . .