descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1948 English Publisher:Massachusetts Medical SocietyJournal:New England Journal of Medicine, volume 238, pages 469-470 (issn: 0028-4793, eissn: 1533-4406,

Authors: John H. CaptainJr. Moyer;

doi: 10.1056/nejm194804012381405

pmid: 18905436

Exfoliative Dermatitis Due to Codeine

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Abstract

CODEINE has been in use as a narcotic since 1832,1 when it was first extracted from opium. Chemically, it is the methyl ester of morphine2 containing a phenanthrine nucleus.3 Today it is used in massive amounts, especially in sanatoriums, and yet drug eruptions due to sensitivity to this agent are extremely rare. Seidmann1 stated that up to 1943 only 10 such cases had been reported in the literature. Since then at least 2 additional cases have been reported. The following case is presented because of the severity of both the skin and systemic manifestations. Case Report A 34-year-old man was . . .

Keywords

Codeine, Dermatitis, Exfoliative

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