Photodynamic Diagnosis–Assisted Transurethral Resection — Lights Out?
Copyright policy )Photodynamic Diagnosis–Assisted Transurethral Resection — Lights Out?
In a randomized trial and accompanying cost-effectiveness analysis, conducted in people with suspected urothelial carcinoma of the bladder, Heer at al.1 in this issue of NEJM Evidence compare transurethral resection aided by intravesical installation of a photosensitizer with the same procedure guided by standard white light. The study's main finding was that the photosensitizer-based approach was not associated with a reduction of time to recurrence of tumor. Moreover, patients undergoing the photosensitizer-based procedure had only a small absolute risk reduction (3.8 percentage points; 95% confidence interval [CI], -13.4 to 6.6) of tumor recurrence in the trial time frame.
- University of Minnesota Morris United States
- Emory University United States
Carcinoma, Transitional Cell, Photosensitizing Agents, Urinary Bladder Neoplasms, Urinary Bladder, Humans, Neoplasm Recurrence, Local, Randomized Controlled Trials as Topic
Carcinoma, Transitional Cell, Photosensitizing Agents, Urinary Bladder Neoplasms, Urinary Bladder, Humans, Neoplasm Recurrence, Local, Randomized Controlled Trials as Topic
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