Cornea pseudoguttata is the term applied to a temporary, completely reversible lesion of the corneal endothelium during inflammations of the anterior segment of the eye. The posterior specular area of the cornea reveals numerous, partially confluent, dark holes of different sizes. At examination with the specular microscope these holes correspond to intra- and intercellular changes in the endothelial mosaic. It appears that the clinical picture of cornea pseudoguttata is caused by both the edema of the endothelial cells and the looseness of the structure of the endothelial layer due to inter- and subcellular accumulations of fluid.