Antitubercular and Antiplasmodial Constituents ofAbrus precatorius

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2004 English Publisher:Georg Thieme Verlag KGJournal:Planta Medica, volume 70, pages 276-278 (issn: 0032-0943, eissn: 1439-0221,

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Authors: Chutima, Limmatvapirat; Sinenart, Sirisopanaporn; Prasat, Kittakoop;

doi: 10.1055/s-2004-818924

pmid: 15114511

Antitubercular and Antiplasmodial Constituents ofAbrus precatorius

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Abstract

A known isoflavanquinone, abruquinone B ( 1), and a new derivative, abruquinone G ( 2), were isolated from the aerial parts of Abrus precatorius. Chemical structures of these compounds were elucidated by spectral analyses. While 1 exhibited antitubercular, antiplasmodial and cytotoxic activities, compound 2 showed mild antiviral and cytotoxic activities.

Related Organizations

Silpakorn University
Thailand
National Center for Genetic Engineering and Biotechnology
Thailand

Keywords

Plant Extracts, Plasmodium falciparum, Antitubercular Agents, Herpesvirus 1, Human, Microbial Sensitivity Tests, Mycobacterium tuberculosis, Plant Components, Aerial, Antiviral Agents, Isoflavones, Antimalarials, Abrus, Chlorocebus aethiops, Animals, Vero Cells, Phytotherapy

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