Antifibrinolytic agents in cardiac surgery: Current controversies
Copyright policy )Antifibrinolytic agents in cardiac surgery: Current controversies
Antifibrinolytic agents play a prominent role in adult cardiac surgery. This article is a review of the modern published experience of antifibrinolytic agent use in adult cardiac surgery. The use of tranexamic acid, epsilon-aminocaproic acid, and aprotinin is examined during primary cardiac surgery, deep hypothermic circulatory arrest, reoperative cardiac surgery, and off-pump coronary artery bypass surgery. In addition, the issues of vein graft patency and hypersensitivity reaction in the presence of antifibrinolytic agents are examined.
- Emory University United States
Heart Valve Prosthesis Implantation, Male, Cardiopulmonary Bypass, Dose-Response Relationship, Drug, Prognosis, Risk Assessment, Severity of Illness Index, Survival Analysis, Antifibrinolytic Agents, Drug Administration Schedule, Perioperative Care, Postoperative Complications, Treatment Outcome, Cardiovascular Diseases, Thromboembolism, Humans, Female, Cardiac Surgical Procedures, Coronary Artery Bypass, Randomized Controlled Trials as Topic
Heart Valve Prosthesis Implantation, Male, Cardiopulmonary Bypass, Dose-Response Relationship, Drug, Prognosis, Risk Assessment, Severity of Illness Index, Survival Analysis, Antifibrinolytic Agents, Drug Administration Schedule, Perioperative Care, Postoperative Complications, Treatment Outcome, Cardiovascular Diseases, Thromboembolism, Humans, Female, Cardiac Surgical Procedures, Coronary Artery Bypass, Randomized Controlled Trials as Topic
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