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Intraoperative Coronary Thrombosis With Aprotinin in the Prebypass Period

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2007Publisher:Elsevier BVJournal:Journal of Cardiothoracic and Vascular Anesthesia, volume 21, pages 558-560 (issn: 1053-0770,

Authors: Donald S. Esmore; Donald S. Esmore; Paul S. Myles;

doi: 10.1053/j.jvca.2007.04.010

pmid: 17678784

Intraoperative Coronary Thrombosis With Aprotinin in the Prebypass Period

- Summary
- Subjects
- Metrics

Abstract

h EOPERATIVE AND OTHER COMPLEX cardiac operations are typically accompanied by prophylactic antifirinolytic therapy to reduce excessive bleeding and transfusion equirements.1,2 However, recent studies have continued the oncern that antifibrinolytic drugs may contribute to thrombotic omplications.3,4 A case of acute coronary artery thrombosis mmediately after aprotinin administration in an elderly male ndergoing repeat coronary artery bypass graft (CABG) surery is presented.

Related Organizations

Monash University
Australia
The Alfred Hospital
Australia

Keywords

Male, Serine Proteinase Inhibitors, Heparin, Coronary Thrombosis, Blood Loss, Surgical, Coronary Stenosis, Coronary Angiography, Aprotinin, Fibrinolytic Agents, Humans, Coronary Artery Bypass, Infusions, Intravenous, Intraoperative Complications, Aged, Follow-Up Studies

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