The location of HII regions, which indicates the locus of present star formation in galaxies, is analyzed for a large collection of 110 irregular galaxies (Irr) imaged in H$��$ and nearby continuum. The analysis is primarily by visual inspection, although a two-dimensional quantitative measure is also employed. The two different analyses yield essentially identical results. HII regions appear preferentially at the edges of the light distribution, predominantly on one side of the galaxy, contrary to what is expected from stochastic self-propagating star formation scenarios. This peculiar distribution of star forming regions cannot be explained by a scenario of star formation triggered by an interaction with extragalactic gas, or by a strong one-armed spiral pattern.

28 pages, four figures, accepted for publication in MNRAS