T-Lymphocyte Subsets in Adult Coeliac Disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1983 English Publisher:Portland Press Ltd.Journal:Clinical Science, volume 65, pages 89-90 (issn: 0143-5221, eissn: 1470-8736,

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Authors: G R, Corazza; P, Tabacchi; M, Frisoni; M, Londei; D, Bastia; G, Gasbarrini;

doi: 10.1042/cs0650089

pmid: 6221857

T-Lymphocyte Subsets in Adult Coeliac Disease

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Abstract

1. As a defect of suppressor function has been hypothesized in the pathogenesis of coeliac disease, we measured, by monoclonal antibodies, the inducer/suppressor T-cell ratio in adult coeliac disease. 2. No statistical difference was observed between coeliac patients and healthy controls, irrespective of treatment and HLA status. 3. These results do not show an imbalance in the inducer/suppressor T-cell ratio in coeliac disease.

Keywords

Adult, Celiac Disease, HLA Antigens, T-Lymphocytes, Antibodies, Monoclonal, Humans, T-Lymphocytes, Regulatory, HLA-B8 Antigen

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