
doi: 10.1042/bst0360263
pmid: 18363570
Recent studies of some proteins involved in the formation of focal adhesions are described. These include fibronectin, integrins, talin, Dok1 and filamin. Emphasis is placed on features that facilitate regulated assembly of complexes; these include a modular construction and flexible regions that provide interaction sites whose affinity can be adjusted by conformational masking and phosphorylation.
Talin, Integrins, Protein Conformation, Filamins, Microfilament Proteins, RNA-Binding Proteins, Phosphoproteins, Models, Biological, Fibronectins, DNA-Binding Proteins, Contractile Proteins, Cell Adhesion, Humans, Protein Binding
Talin, Integrins, Protein Conformation, Filamins, Microfilament Proteins, RNA-Binding Proteins, Phosphoproteins, Models, Biological, Fibronectins, DNA-Binding Proteins, Contractile Proteins, Cell Adhesion, Humans, Protein Binding
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