Control of mRNA stability in eukaryotes

descriptionPublicationkeyboard_double_arrow_right Article 20 Jan 2006 United Kingdom English Publisher:Portland Press Ltd.Journal:Biochemical Society Transactions, volume 34, pages 30-34 (issn: 0300-5127, eissn: 1470-8752,

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Authors: Newbury SF;

doi: 10.1042/bst0340030

pmid: 16246172

Control of mRNA stability in eukaryotes

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Abstract

mRNA turnover plays a key role in the control of gene expression. Recent work has shown that proteins involved in mRNA turnover are located in multicomponent complexes which are tightly regulated. The control of mRNA stability is also intimately linked with translational processes. This article reviews the pathways and enzymes that control mRNA turnover in eukaryotic cells and discusses their mechanisms of control.

Country

United Kingdom

Related Organizations

University of Newcastle Australia
Australia
Newcastle University
United Kingdom

Keywords

Eukaryotic Cells, Saccharomyces cerevisiae Proteins, Gene Expression Regulation, Protein Biosynthesis, RNA Stability, Exoribonucleases, Animals, Drosophila Proteins, RNA, Messenger

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