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IgG Fe receptors that resemble class I major histocompatibility complex antigens

Authors: N E, Simister;

IgG Fe receptors that resemble class I major histocompatibility complex antigens

Abstract

(1) The intestinal Fc receptors of neonatal rats and mice consists of beta 2m and an alpha-chain that is similar to those of MHC class I and CD1 antigens. (2) Mouse and rat FcRns are highly conserved. There are no amino acid substitutions in the 90 amino acid alpha 3 domain, and only one in the 40 amino acid cytoplasmic tail. (3) Despite its similarity to class I MHC antigens, the mouse FcRn alpha-chain is encoded outside the MHC, on chromosome 7.

Related Organizations
Keywords

Sequence Homology, Amino Acid, Histocompatibility Antigens Class I, Molecular Sequence Data, Receptors, IgG, Chromosome Mapping, Rats, Antigens, CD1, Mice, Animals, Newborn, Antigens, CD, Pregnancy, Immunoglobulin G, HLA-A2 Antigen, Animals, Humans, Female, Amino Acid Sequence, Intestinal Mucosa, Maternal-Fetal Exchange, Conserved Sequence

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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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