
doi: 10.1042/bst0210973
pmid: 7510654
(1) The intestinal Fc receptors of neonatal rats and mice consists of beta 2m and an alpha-chain that is similar to those of MHC class I and CD1 antigens. (2) Mouse and rat FcRns are highly conserved. There are no amino acid substitutions in the 90 amino acid alpha 3 domain, and only one in the 40 amino acid cytoplasmic tail. (3) Despite its similarity to class I MHC antigens, the mouse FcRn alpha-chain is encoded outside the MHC, on chromosome 7.
Sequence Homology, Amino Acid, Histocompatibility Antigens Class I, Molecular Sequence Data, Receptors, IgG, Chromosome Mapping, Rats, Antigens, CD1, Mice, Animals, Newborn, Antigens, CD, Pregnancy, Immunoglobulin G, HLA-A2 Antigen, Animals, Humans, Female, Amino Acid Sequence, Intestinal Mucosa, Maternal-Fetal Exchange, Conserved Sequence
Sequence Homology, Amino Acid, Histocompatibility Antigens Class I, Molecular Sequence Data, Receptors, IgG, Chromosome Mapping, Rats, Antigens, CD1, Mice, Animals, Newborn, Antigens, CD, Pregnancy, Immunoglobulin G, HLA-A2 Antigen, Animals, Humans, Female, Amino Acid Sequence, Intestinal Mucosa, Maternal-Fetal Exchange, Conserved Sequence
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