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Radioimmunoassay of colchicine

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1975 English Publisher:Portland Press Ltd.Journal:Biochemical Journal, volume 151, pages 413-415 (issn: 0264-6021,

Authors: Duprey F; Bohuon C; Boudène C;

doi: 10.1042/bj1510413

pmid: 1218086

pmc: PMC1172372

Radioimmunoassay of colchicine

- Summary
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Abstract

Antibodies to cholchicine were raised in rabbits after injection of N-desacetylthiocolchicine conjugated to bovine serum albumin. Antisera diluted 1:100 bound 50% of 1.6ng of [3H]colchicine. Cross-reaction of the antisera with colchicine derivatives and other drugs was measured and a radioimmunoassay of colchicine in biological fluids was proposed.

Keywords

Antibody Specificity, Chromatography, Gel, Radioimmunoassay, Animals, Rabbits, Colchicine, Haptens

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	34
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%