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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Food & Functionarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Food & Function
Article . 2025 . Peer-reviewed
License: Royal Society of Chemistry Licence to Publish
Data sources: Crossref
Food & Function
Article . 2025
Data sources: Europe PubMed Central
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Multi-strategy profiling identifies limonin's dual role in gout: restoring uric acid homeostasis and suppressing inflammatory response

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2025 English Publisher:Royal Society of Chemistry (RSC)Journal:Food & Function, volume 16, pages 9,572-9,592 (issn: 2042-6496, eissn: 2042-650X, Copyright policy )
Authors: Minjie Zeng; Mei Zhong; Xiaomei Zhong; Yiqian Zhang; Xueting Chen; Jing Lin; Ying Zhang; +3 Authors

doi: 10.1039/d5fo02484f

pmid: 41288573

Multi-strategy profiling identifies limonin's dual role in gout: restoring uric acid homeostasis and suppressing inflammatory response

Abstract

Limonin restored UA homeostasis by simultaneously regulating UA excretion and production. It alleviated hepatorenal damage and inflammation by binding to AMPK, thereby suppressing downstream inflammatory activation.

Related Organizations
Keywords

Male, Limonins, Rats, Sprague-Dawley, Inflammation, Disease Models, Animal, Gout, Anti-Inflammatory Agents, NF-kappa B, Animals, Homeostasis, Humans, Uric Acid, Rats

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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Average
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