Effects of (−)-epicatechin on hepatic triglyceride metabolism

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2024 English Publisher:Royal Society of Chemistry (RSC)Journal:Food & Function, volume 15, pages 326-337 (issn: 2042-6496, eissn: 2042-650X,

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Authors: Zahra Mostofinejad; Eleonora Cremonini; Jiye Kang; Patricia I. Oteiza;

doi: 10.1039/d3fo03666a

pmid: 38086683

Effects of (−)-epicatechin on hepatic triglyceride metabolism

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Abstract

(−)-Epicatechin (EC) consumption promotes changes in liver lipid homeostasis by increasing hepatic TG levels and DGAT2 and PPARα expression in mice. In human HepG2 cells, EC and its metabolites did not replicate these effects on TG accumulation.

Related Organizations

University of California, Davis
United States

Keywords

Mice, Liver, Non-alcoholic Fatty Liver Disease, Body Weight, Humans, Animals, Fatty Acids, Nonesterified, Lipid Metabolism, Catechin, Triglycerides

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