Stereocontrolled total synthesis of Resolvin D4 and 17(R)-Resolvin D4

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2023 English Publisher:Royal Society of Chemistry (RSC)Journal:Organic & Biomolecular Chemistry, volume 21, pages 1,667-1,673 (issn: 1477-0520, eissn: 1477-0539,

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Authors: Robert Nshimiyimana; Stephen J. Glynn; Charles N. Serhan; Nicos A. Petasis;

doi: 10.1039/d2ob01697d

pmid: 36345797

pmc: PMC9974885

Stereocontrolled total synthesis of Resolvin D4 and 17(R)-Resolvin D4

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Abstract

We describe the stereocontrolled synthesis of Resolvin D4 and 17(R)-Resolvin D4. These molecules possess protective activities in resolving inflammation.

Related Organizations

University of California System
United States

Keywords

Inflammation, Docosahexaenoic Acids, Fatty Acids, Unsaturated, Humans, Stereoisomerism

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