Synthesis of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins
Copyright policy ) Ivette Morales-Salazar; Flora P. Montes-Enríquez; Carlos E. Garduño-Albino; M. A. García-Sánchez; Ilich A. Ibarra; Yareli Rojas-Aguirre; Montserrat Elemi García-Hernández; +5 Authors
Ivette Morales-Salazar; Flora P. Montes-Enríquez; Carlos E. Garduño-Albino; M. A. García-Sánchez; Ilich A. Ibarra; Yareli Rojas-Aguirre; Montserrat Elemi García-Hernández; Rosa Elena Sarmiento-Silva; Sofía Lizeth Alcaraz-Estrada; Erik Díaz-Cervantes; Eduardo González-Zamora; Alejandro Islas-Jácome;
Synthesis of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins
Six polyheterocycles were studied in vitro against human SARS-CoV-2 finding that one of them exhibited significant activity at initial infection stages, showing prophylactic potential. A second one showed both, prophylactic and therapeutic activity.
- National Autonomous University of Mexico Mexico
- Universidad Da Vinci Mexico
- Universidad de Guanajuato Mexico
- Universidad Autónoma Metropolitana Mexico
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 6
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