Nobiletin mitigates NAFLD via lipophagy and inflammation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2022 English Publisher:Royal Society of Chemistry (RSC)Journal:Food & Function, volume 13, pages 10,186-10,199 (issn: 2042-6496, eissn: 2042-650X,

Copyright policy )

Authors: Xushan Yang; Yudi Deng; Yali Tu; Dongliang Feng; Wenzhen Liao;

doi: 10.1039/d2fo01682f

pmid: 36111578

Nobiletin mitigates NAFLD via lipophagy and inflammation

- Summary
- Subjects
- Metrics

Abstract

Nobiletin was found to mitigate nonalcoholic fatty liver disease by enhancing TFEB-mediated lipophagy, alleviating NLRP3 inflammasome and modulating macrophages polarization.

Related Organizations

Southern Medical University
China (People's Republic of)

Keywords

Inflammation, Inflammasomes, Fatty Acids, Nonesterified, Diet, High-Fat, Flavones, Mice, Inbred C57BL, Mice, Apolipoproteins E, Liver, Non-alcoholic Fatty Liver Disease, NLR Family, Pyrin Domain-Containing 3 Protein, Autophagy, Animals, Eosine Yellowish-(YS), Hematoxylin

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	13
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%