Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2020 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Society Reviews, volume 49, pages 7,710-7,729 (issn: 0306-0012, eissn: 1460-4744,

Copyright policy )

Authors: Eloah Latocheski; Gean M. Dal Forno; Thuany M. Ferreira; Bruno L. Oliveira; Gonçalo J. L. Bernardes; Josiel B. Domingos;

doi: 10.1039/d0cs00630k

pmid: 33026001

Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions

- Summary
- Subjects
- Metrics

Abstract

This review assesses the mechanistic aspects of transition metal-mediated uncaging reactions, with the goal of aiding the rational development of new caging groups/catalysts for chemical biology and drug-delivery applications.

Related Organizations

University of Lisbon
Portugal
University of Cambridge
United Kingdom
Gulbenkian Institute for Molecular Medicine
Portugal
INSTITUTO DE MEDICINA MOLECULAR
Portugal
Universidade Federal de Santa Catarina
Brazil

Keywords

Molecular Structure, Transition Elements, Organic Chemicals

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	54
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%