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Chemical Communications
Article . 2020 . Peer-reviewed
License: CC BY NC
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Chemical Communications
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License: CC BY NC
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Chemical Communications
Article . 2021
Data sources: Europe PubMed Central
https://dx.doi.org/10.1039/d0c...
Article
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Article . 2020
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A caged E3 ligase ligand for PROTAC-mediated protein degradation with light

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2020 United Kingdom English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 56, pages 5,532-5,535 (issn: 1359-7345, eissn: 1364-548X, Copyright policy )Funded by:UKRI | NPIF EPSRC Doctoral - Imp..., UKRI | LSI Doctoral Training Cen..., UKRI | Programming GPCR signalli... +1 projects
Authors: Cyrille S. Kounde; Maria M. Shchepinova; Charlie N. Saunders; Marcel Muelbaier; Mark D. Rackham; John D. Harling; Edward W. Tate;

doi: 10.1039/d0cc00523a

pmid: 32297626

handle: 10044/1/77762

A caged E3 ligase ligand for PROTAC-mediated protein degradation with light

Abstract

Caging of a widely used Von Hippel Lindau E3 ligase ligand for targeted protein degradation with PROTACs allows light-activated proteolysis.

Country
United Kingdom
Related Organizations
Keywords

570, Light, Molecular Structure, Ubiquitin-Protein Ligases, Organic Chemistry, Ligands, 615, Proteolysis, Humans, 03 Chemical Sciences, HeLa Cells

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 107
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
107
Top 1%
Top 10%
Top 1%
hybrid