A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2018 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Science, volume 9, pages 4,937-4,941 (issn: 2041-6520, eissn: 2041-6539,

Copyright policy )Funded by:NIH | The Neuroproteomics and N..., NIH | National Resource for Apl..., NIH | Study Exocytosis in the R... +1 projects

Authors: Theresa M. Welle; Kristen Alanis; Michelle L. Colombo; Jonathan V. Sweedler; Mei Shen;

doi: 10.1039/c8sc01131a

pmid: 29938020

pmc: PMC5994989

A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes

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Abstract

Extra-synaptic exocytosis is an essential component of cellular communication. A knowledge gap exists in the exocytosis of the non-redox active transmitter acetylcholine. Using the nano-interface between two immiscible electrolyte solutions and scanning electrochemical microscopy, a high resolution spatiotemporal study of acetylcholine exocytosis is shown from individual neuronal soma.

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Keywords

Chemistry

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