Magnetic nanoparticles loaded with functional RNA nanoparticles

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2018 English Publisher:Royal Society of Chemistry (RSC)Journal:Nanoscale, volume 10, pages 17,761-17,770 (issn: 2040-3364, eissn: 2040-3372,

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Authors: Melissa Cruz-Acuña; Justin R. Halman; Kirill A. Afonin; Jon Dobson; Carlos Rinaldi;

doi: 10.1039/c8nr04254c

pmid: 30215080

Magnetic nanoparticles loaded with functional RNA nanoparticles

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Abstract

RNA nanoparticle constructs complexed with polyethylenimine-coated iron oxide nanoparticles are protected from enzymatic degradation and knockdown is amplified by magnetic stimulus in mammalian cells.

Related Organizations

University of North Carolina at Chapel Hill
United States
University of North Carolina at Charlotte
United States
University of Florida
United States

Keywords

Microscopy, Atomic Force, Transfection, Ferric Compounds, Magnetics, Drug Delivery Systems, Microscopy, Electron, Transmission, Cell Line, Tumor, Humans, Polyethyleneimine, RNA, Magnetite Nanoparticles

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