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Human histone demethylase KDM6B can catalyse sequential oxidations

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2018 United Kingdom English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 54, pages 7,975-7,978 (issn: 1359-7345, eissn: 1364-548X, Copyright policy )Funded by:UKRI | Structural, Mechanistic a..., UKRI | Industrial Doctorate Cent..., UKRI | Evolution of Oxygen Sensi... +3 projects
Authors: Richard J. Hopkinson; Gareth W. Langley; Roman Belle; Louise J. Walport; Kate Dunne; Martin Münzel; Eidarus Salah; +3 Authors
APC: 1,152.8 EUR

doi: 10.1039/c8cc04057e

pmid: 29961803

pmc: PMC6044289

handle: 2381/42424 , 10044/1/63279

Human histone demethylase KDM6B can catalyse sequential oxidations

Abstract

Biochemical studies on the histone lysyl demethylase KDM6B reveal it is capable of catalysing reactions on multiple lysine analogues, forming de-alkylated, hydroxylated, and oxidised products.

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United Kingdom
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Keywords

Jumonji Domain-Containing Histone Demethylases, PROTEINS, JMJD3, 610, Matrix-Assisted Laser Desorption-Ionization, Humans, 5-METHYLCYTOSINE, Amino Acid Sequence, MACROPHAGES, GENE-EXPRESSION, Science & Technology, Multidisciplinary, Spectrometry, Lysine, Organic Chemistry, DNA, Mass, 540, Chemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Physical Sciences, Biocatalysis, 03 Chemical Sciences, Peptides, Oxidation-Reduction

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 5
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
Green
hybrid
Related to Research communities
UArctic