Ring closing metathesis of unprotected peptides

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2017 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 53, pages 9,769-9,772 (issn: 1359-7345, eissn: 1364-548X,

Copyright policy )Funded by:ARC | New metal catalysed tande...

Authors: Ellen C. Gleeson; W. Roy Jackson; Andrea J. Robinson;

doi: 10.1039/c7cc04100d

pmid: 28815236

Ring closing metathesis of unprotected peptides

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Abstract

Brønsted acid masking of unprotected peptide sequences facilitates high yielding Ru-alkylidene catalysed RCM to cyclic dicarba peptidomimetics in solution.

Related Organizations

Monash University
Australia
Sigma Clermont
France
Monash University, Clayton campus
Australia

Keywords

Molecular Conformation, Organometallic Compounds, Alkenes, Peptides, Ruthenium

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