New insights into the pretargeting approach to image and treat tumours

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2016Embargo end date: 01 Jan 2016 Switzerland, Germany English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Society Reviews, volume 45, pages 6,415-6,431 (issn: 0306-0012, eissn: 1460-4744,

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Authors: Malay Patra; Kristof Zarschler; Hans-Jürgen Pietzsch; Holger Stephan; Gilles Gasser;

doi: 10.1039/c5cs00784d , 10.5167/uzh-134643

pmid: 27722526

New insights into the pretargeting approach to image and treat tumours

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Abstract

This tutorial review describes the fundamental concept of tumour pretargeting, highlights the historical as well as recent advances of this strategy and discusses the advantages and disadvantages of different available variations.

Countries

Switzerland, Germany

Related Organizations

Helmholtz-Zentrum Dresden-Rossendorf
Germany
University of Zurich
Switzerland

Keywords

10120 Department of Chemistry, Immunoconjugates, Antibodies, Monoclonal, 1600 General Chemistry, Radioimmunotherapy, Radioimmunodetection, Antigens, Neoplasm, Neoplasms, 540 Chemistry, Animals, Humans

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	100
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%