Polymorphic cross-seeding amyloid assemblies of amyloid-β and human islet amyloid polypeptide

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015 English Publisher:Royal Society of Chemistry (RSC)Journal:Physical Chemistry Chemical Physics, volume 17, pages 23,245-23,256 (issn: 1463-9076, eissn: 1463-9084,

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Authors: Mingzhen, Zhang; Rundong, Hu; Hong, Chen; Yung, Chang; Jie, Ma; Guizhao, Liang; Jingyan, Mi; +2 Authors

doi: 10.1039/c5cp03329b

pmid: 26283068

Polymorphic cross-seeding amyloid assemblies of amyloid-β and human islet amyloid polypeptide

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Abstract

Epidemiological studies have shown that the development of Alzheimer's disease (AD) is associated with type 2 diabetes (T2D), but it still remains unclear how AD and T2D are connected.

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Keywords

Amyloid beta-Peptides, Protein Conformation, Humans, Molecular Dynamics Simulation, Islet Amyloid Polypeptide

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