Overcoming cisplatin resistance in chemotherapy by biomineralization

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2013 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 49, page 4,932 (issn: 1359-7345, eissn: 1364-548X,

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Authors: Wei, Chen; Yun, Xiao; Xueyao, Liu; Yanhong, Chen; Jiaojiao, Zhang; Xurong, Xu; Ruikang, Tang;

doi: 10.1039/c3cc41872c

pmid: 23604226

Overcoming cisplatin resistance in chemotherapy by biomineralization

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Abstract

Nano-solidified intermedias (NSI) of cisplatin were prepared via biomineralization and applied to reverse the drug resistance of cancers in vitro and in vivo by an alternative internalization pathway.

Related Organizations

Zhejiang Ocean University
China (People's Republic of)

Keywords

Cell Survival, Drug Resistance, Neoplasm, Cell Line, Tumor, Carbonates, Humans, Antineoplastic Agents, Cisplatin, Endocytosis, Phosphates

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