Tabun scavengers based on hydroxamic acid containing cyclodextrins

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2013 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 49, page 3,425 (issn: 1359-7345, eissn: 1364-548X,

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Authors: Florian, Brandhuber; Michael, Zengerle; Luzian, Porwol; Anne, Bierwisch; Marianne, Koller; Georg, Reiter; Franz, Worek; +1 Authors

doi: 10.1039/c3cc41290c

pmid: 23503705

Tabun scavengers based on hydroxamic acid containing cyclodextrins

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Abstract

Arrangement of several hydroxamic acid-derived substituents along the cavity of a cyclodextrin ring leads to compounds that detoxify tabun in TRIS-HCl buffer at physiological pH and 37.0 °C with half-times as low as 3 min.

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