Cellular transport and homeostasis of essential and nonessential metals

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2012 English Publisher:Oxford University Press (OUP)Journal:Metallomics, volume 4, page 593 (issn: 1756-5901, eissn: 1756-591X,

Copyright policy )Funded by:NIH | Training Program in Envir..., NIH | Mechanisms of Methylmercu...

Authors: Ebany J, Martinez-Finley; Sudipta, Chakraborty; Stephanie J B, Fretham; Michael, Aschner;

doi: 10.1039/c2mt00185c

pmid: 22337135

pmc: PMC4936191

Cellular transport and homeostasis of essential and nonessential metals

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Abstract

Metals can have a number of detrimental or beneficial effects in the cell, but first they must get in. Organisms have evolved transport mechanisms to get metals that are required, or essential into the cell. Nonessential metals often enter the cell through use of the machinery provided for essential metals. Much work has been done to advance our understanding of how these metals are transported across plasma and organelle membranes. This review provides an overview of essential and nonessential metal transport and homeostatic processes.

Related Organizations

VANDERBILT UNIVERSITY
Vanderbilt University Medical Center
United States
VANDERBILT UNIVERSITY

Keywords

Metals, Cells, Animals, Homeostasis, Humans, Biological Transport

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