Functionalization, re-functionalization and rejuvenation of ssDNA nanotemplates

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2012 Taiwan English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 48, page 4,902 (issn: 1359-7345, eissn: 1364-548X,

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Authors: Lin, Ming-Yu; Ho, Fu Han; Yang, Chung-Yao; Yeh, J.Andrew; Yang, Yuh-Shyong;

doi: 10.1039/c2cc30748k

pmid: 22499154

Functionalization, re-functionalization and rejuvenation of ssDNA nanotemplates

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Abstract

Single-stranded DNA (ssDNA) with repetitive sequence was demonstrated to be a versatile nanotemplate for introducing biological activity in a self-assembled manner. Re-functionalization and rejuvenation of the ssDNA nanotemplate were achieved under mild biological conditions without using high temperature and strong alkaline treatment to denature DNA.

Country

Taiwan

Related Organizations

National Taiwan University of Science and Technology
Taiwan
National Applied Research Laboratories
Taiwan
National Tsing Hua University
Taiwan
National Chiao Tung University
Taiwan

Keywords

Silicon, Temperature, Biotin, DNA, Single-Stranded, DNA, NANOWIRES, Nucleic Acid Denaturation, SCAFFOLDS, Nanostructures, Nanotechnology, ROLLING CIRCLE AMPLIFICATION, Horseradish Peroxidase

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